A chronic systemic disease characterised by inflammatory changes in joints & related structures that results in crippling deformities. Diseases primarily affecting the synovium & adjacent tissues. Rheumatoid arthritis is a chronic systemic inflammatory disorder that may affect many tissues and organs, but principally attacks the joints producing a inflammatory synovitis that often read more [...]

Still’s Disease Chronic, inflammatory, systemic disease which may cause joint or connective tissue damage & visceral lesions throughout the body characterised by fever, rash, hepato-spleenomegaly & arthritis in children. It is a persistent inflammatory arthritis (> 6 weeks) that begins before age 16 for which no specific cause can be found. ETIOLOGY of Juvenile Rheumatoid Arthritis • Exact cause is unknown. • Evidence points to autoimmune aetiology. • Associated with physical read more [...]

Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body attacks its own cells. Autoimmune diseases are a major cause of immune-mediated diseases, and are commonly referred to as Autoimmune and Inflammatory Diseases (AIID). Gender influence Nearly 79% of autoimmune disease patients in the USA are women. Also they tend to appear during or shortly after puberty. It is not known why this is the case, read more [...]

Systemic lupus erythematosus (SLE or lupus, pronounced /s??st?m?k ?lu?p?s ??r??θim??to?s?s/) is a chronic autoimmune disease that can be fatal, though with recent medical advances, fatalities are becoming increasingly rare. As with other autoimmune diseases, the immune system attacks the body’s cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous read more [...]