Agranulocytosis is an acute condition involving a severe and dangerous leukopenia particularly of neutrophils causing a neutropenia in the circulating blood.[1][2] The meaning of the term can be worked out from the etymology with the prefix ‘a’ denoting a reduction in the number of granulocytes in the blood stream [3]. Concentrations of granulocytes (a class that includes neutrophils, basophils and eosinophils) can often drop to below 500 cells/mm³ of blood), less than a sixth of the reference read more [...]

Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low platelet count (thrombocytopenia) of no known cause (idiopathic). As most causes appear to be related to antibodies against platelets, it is also known as immune thrombocytopenic purpura. Although most cases are asymptomatic, very low platelet counts can lead to a bleeding diathesis and purpura. Epidemiology The incidence of ITP is 50–100 new cases per million per year, with children accounting for half of that amount. More read more [...]

Hodgkin’s lymphoma, also known as Hodgkin’s disease, is a type of lymphoma first described by Thomas Hodgkin in 1832. Hodgkin’s lymphoma is characterized clinically by the orderly spread of disease from one lymph node group to another and by the development of systemic symptoms with advanced disease. Pathologically, the disease is characterized by the presence of Reed-Sternberg cells (RS cells). Hodgkin’s lymphoma was one of the first cancers to be cured by radiation. Later it was one of read more [...]

Leukemia or leukaemia (Greek leukos λευκ?ς, “white”; aima α?μα, “blood”) is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes). Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases called hematological neoplasms. Classification of Leukemia Leukemia is clinically and pathologically subdivided into read more [...]